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About Kyazma®

Kyazma was founded in the spring of 2003. The company's goal is to serve the genomics research community with software and courses that may assist scientists in getting the most out of their genetic mapping experiments.

Product

  • JoinMap® 4 : Software for the calculation of genetic linkage maps in experimental populations of diploid species

  • MapQTL® 6 : Software for the mapping of quantitative trait loci in experimental populations
    • New features

      1. The Haley & Knott regression approximation to maximum likelihood interval and MQM mapping was added. Advantages of the regression approach are a magnitude higher speed and reduced use of RAM memory, while the quality of the approximation is generally quite good.

      2. Three population types that can be analysed were added
        DH2: doubled haploid population drawn from an F2, one doubled gamete from one F2 plant
        BCpxFy: advanced backcross inbred line family (any generation)
        IMxFy: advanced intermated inbred line family (any generation)

      3. Simple experimental design (e.g. blocking) and covariates can be analysed jointly with interval and MQM mapping.

      4. Traits observed in multiple populations can be analysed combined over the populations with interval and MQM mapping. (This feature at the automatic cofactor selection will follow later.)

    • features
      1. 기존의 MS-Window 사용자들이 직관적으로 사용할 수 있는 사용자 인터페이스
      2. 실험 집단 형태: BC1, F2, RIL, F1-derived and F2-derived DH, outbreeder full-sib family

      3. quantitative trait data의 유연한 layout, molecular marker의 표현형, (계산되지 않은)linkage map; map과 molecular marker data 파일을 가진 명백한 text 파일의 input은 JoinMap ®과 호환 가능

      4. interval mapping, enhanced for an outbreeder full-sib family to 'all-markers' mapping, employing the segregation information of all linked markers, each of which may follow a different segregation type, with two up to four alleles
      5. MQM mapping, in which markers are used as cofactors to absorb the effects of nearby QTLs, thereby increasing the power for mapping other segregating QTLs; it may even enable the separation and mapping of linked QTLs
      6. nonparametric mapping with the Kruskal-Wallis rank sum test per marker to assess the segregation of QTLs for non-normally distributed data
      7. MQM mapping cofactors set을 쉽게 얻기 위해 자동으로 선택
      8. data 오차의 가정 없이 interval mapping의 유의적인 level을 결정하기 위한 permutation test 기능

      9. Feature를 가지고 있는 map chart를 MS-Word와 MS-PowerPoint로 옮기는 기능

      10. PDF로 만들어진 사용자 manual 제공

      11. InstallShield 를 이용하여 손쉽게 설치

Manual file

kyazma (last edited 2012-03-17 17:24:19 by localhost)










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